Carbon monoxide (CO) exposure from ultralow , low and high CO delivery commercial cigarettes was examined under controlled smoking conditions. Seven chronic smokers of mid to high CO delivery commercial cigarettes served in the experiment. CO level increases of 2.10, 5.76 and 7.38 ppm were obtained from ultralow yield (1.6 mg CO delivery), low yield (5.9 mg CO delivery) and high yield (14.3 mg CO delivery) cigarettes, respectively. Subjects achieved significantly higher increases in CO levels from both low and high yield cigarettes than from ultralow yield cigarettes, but increased levels of CO from low and high yield cigarettes were not different from each other. The data suggest that degree of CO absorption by the lungs during a short period of time may limit increases in CO levels obtained from high yield cigarettes.

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